Huaquillas is a town in western El Oro, a province of SW Ecuador. It is the canton seat of the Huaquillas Canton.
Huaquillas is located on the border with Peru. An international bridge that goes over the Zarumilla River connects it with the Peruvian town of Aguas Verdes. Both towns have an intense commercial life and many formal, as well as informal street sellers that sell goods both in US dollars, the only currency in Ecuador, and in Peruvian soles.