Trikala is a city in northwestern Thessaly, Greece. It is the capital of the Trikala Prefecture. Located in the fertile plain of Thessaly in central Greece, modern Trikala is the Homeric Trikka (or Trikki), the birthplace of three of the Argonauts and one of the places touted as the birthplace of Asclepius (Asklepios), who is more often said to have been born at Epidaurus, where his main temple was situated in antiquity. Ruins of an old sanctuary to the physician-god, an Asklepieion, or healing place, are located between the central square and the church of Saint Nicholas (Agios Nikolaos) in Trikala. It is the oldest Aesculapium of Greece - a kind of medical center, from which the worship of Aesculapius gradually spread.
There are other late Hellenistic and Roman period remains, mosaic floors, a stoa and baths. Dominated by its Byzantine fortress on Hellenistic foundations occupying the ancient Acropolis, the picturesque city is divided into two by the river Lithaios. The churches of Agios Demetrios and Agii Anargyri lend more Byzantine character to the modern town.

Attractions

• The Asklepeion at Trikala
• Barousi of Trikala city