Biysk is a city in Altai Krai of Russia. Biysk is the second largest city of the Krai (after Barnaul), with population of 229,412. Biysk is situated in Southwestern Siberia, on the Biya River (not far from its confluence with the Katun River). The city is called "the gates to the Altay Mountains", because of its position comparatively not far from this range. In Biysk there is the beginning of the Chuysky Highway, which goes through the Altai Republic to Russia's border with Mongolia.